{"product_id":"cite4-polyclonal-antibody-bt-ap07717","title":"CITE4 Polyclonal Antibody - BT-AP07717","description":"\u003cp\u003eCITE4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07717-20, BT-AP07717-50, BT-AP07717-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Epigenetics and nuclear signaling; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CITED4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cbp\/p300-interacting transactivator 4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96RK1; Mouse: Q9WUL8; Rat: Q99MA0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cbp\/p300-interacting transactivator 4;MSG1-related protein 2;MRG-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 163732\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239094837427,"sku":"BT-AP07717-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239094870195,"sku":"BT-AP07717-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239094902963,"sku":"BT-AP07717-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e83806e1-83c7-49d2-a985-5d258e0b6342.png?v=1769389046","url":"https:\/\/afsbio.com\/products\/cite4-polyclonal-antibody-bt-ap07717","provider":"AFSBio Inc.","version":"1.0","type":"link"}