{"product_id":"cldn4-rabbit-pab-a12912","title":"CLDN4 Rabbit pAb - A12912","description":"\u003cp\u003eCLDN4 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A12912-20, A12912-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 22kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 18kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1364\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O14493\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; CLDN4\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:2000 - 1:4000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Tight Junctions, Cytoskeleton.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CLDN4\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189540249779,"sku":"A12912-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189540282547,"sku":"A12912-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_7bf1bfb4-80af-420c-b560-d407d9c71bd9.png?v=1766429389","url":"https:\/\/afsbio.com\/products\/cldn4-rabbit-pab-a12912","provider":"AFSBio Inc.","version":"1.0","type":"link"}