{"product_id":"cleaved-caspase-2-p18-g170-polyclonal-antibody-ra23458","title":"Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody - RA23458","description":"Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA23458-50, RA23458-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: caspase 2 (CASP2) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/40000. Not yet tested in other applications.\n\nAlternative Names: CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 835\n\nProtein MW (KDa): 18 or 35\n\nSWISS: P42575\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121204453555,"sku":"RA23458-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121204486323,"sku":"RA23458-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e314110d-090b-418f-9313-397813a7bd08.png?v=1773345199","url":"https:\/\/afsbio.com\/products\/cleaved-caspase-2-p18-g170-polyclonal-antibody-ra23458","provider":"AFSBio Inc.","version":"1.0","type":"link"}