{"product_id":"cleaved-caspase-6-p18-polyclonal-antibody-bz16406","title":"Cleaved-Caspase 6 p18 Polyclonal Antibody-BZ16406","description":"\u003cp\u003eCleaved-Caspase 6 p18 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16406-50, BZ16406-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P55212\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  ELISA: 1\/10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 20,35 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Cleaved-Caspase 6 p18 in various lysates using Cleaved-Caspase 6 p18 antibody., Western blot analysis of Cleaved-Caspase 6 p18 in 293 lysates using Cleaved-Caspase6 p18 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue using Caspase 6 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Western blot analysis of Cleaved-Caspase 6 p18 in 293 lysates treated with Etoposide using Cleaved-Caspase 6 p18 antibody. The Lane on the right is blocked with the synthesized peptide.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Cleaved\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43055903801523,"sku":"BZ16406-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43055903834291,"sku":"BZ16406-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a4ca7e5d-c6f1-41ba-82e4-d49ab7202736.jpg?v=1708086392","url":"https:\/\/afsbio.com\/products\/cleaved-caspase-6-p18-polyclonal-antibody-bz16406","provider":"AFSBio Inc.","version":"1.0","type":"link"}