{"product_id":"cleaved-cd97α-l530-rabbit-pab-es8096","title":"Cleaved-CD97α (L530) rabbit pAb - ES8096","description":"\u003cp\u003eCleaved-CD97α (L530) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8096-50, ES8096-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 1\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: CD97; CD97 antigen; Leukocyte antigen CD97; CD antigen CD97\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human CD97alpha. AA range:481-530\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 55kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 976\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P48960\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Multi-pass membrane protein.; [Adhesion G protein-coupled receptor E5 subunit alpha]: Secreted, extracellular space.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202372100275,"sku":"ES8096-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202372133043,"sku":"ES8096-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_61cc738d-580f-46fa-af94-01f82b40ce8e.png?v=1767127728","url":"https:\/\/afsbio.com\/products\/cleaved-cd97%ce%b1-l530-rabbit-pab-es8096","provider":"AFSBio Inc.","version":"1.0","type":"link"}