{"product_id":"cleaved-cd97alpha-l530-polyclonal-antibody-bt-ap01915","title":"Cleaved-CD97Alpha (L530) Polyclonal Antibody - BT-AP01915","description":"\u003cp\u003eCleaved-CD97Alpha (L530) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01915-20, BT-AP01915-50, BT-AP01915-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ADGRE5 (adhesion G protein-coupled receptor E5) encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of ADGRE5 may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD97\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cleaved-CD97alpha (L530) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 91869\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P48960; Mouse: Q9Z0M6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CD97; CD97 antigen; Leukocyte antigen CD97; CD antigen CD97\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 976\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240208359603,"sku":"BT-AP01915-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240208392371,"sku":"BT-AP01915-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240208425139,"sku":"BT-AP01915-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_090fcc99-9d91-429f-88ff-70baeb1dc6cf.png?v=1769405133","url":"https:\/\/afsbio.com\/products\/cleaved-cd97alpha-l530-polyclonal-antibody-bt-ap01915","provider":"AFSBio Inc.","version":"1.0","type":"link"}