{"product_id":"cleaved-integrin-α5-hc-f42-rabbit-pab-es5944","title":"Cleaved-Integrin α5 HC (F42) rabbit pAb - ES5944","description":"\u003cp\u003eCleaved-Integrin α5 HC (F42) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5944-50, ES5944-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: integrin subunit alpha 5 (ITGA5) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human ITGA5. AA range:23-72\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 92kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3678\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P08648\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Cell surface.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202273403059,"sku":"ES5944-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202273435827,"sku":"ES5944-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_887b9d16-778a-44f4-a9ef-8a38870cc9c5.png?v=1767125547","url":"https:\/\/afsbio.com\/products\/cleaved-integrin-%ce%b15-hc-f42-rabbit-pab-es5944","provider":"AFSBio Inc.","version":"1.0","type":"link"}