{"product_id":"cleaved-integrinalphav-hc-k889-polyclonal-antibody-bt-ap01933","title":"Cleaved-IntegrinAlphaV HC (K889) Polyclonal Antibody - BT-AP01933","description":"\u003cp\u003eCleaved-IntegrinAlphaV HC (K889) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01933-20, BT-AP01933-50, BT-AP01933-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ITGAV\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cleaved-Integrin alphaV HC (K889) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 116038\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P06756; Mouse: P43406\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3685\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240210260147,"sku":"BT-AP01933-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240210292915,"sku":"BT-AP01933-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240210325683,"sku":"BT-AP01933-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8a69a2e7-8ffa-4a82-a5e4-78342ee80160.png?v=1769405160","url":"https:\/\/afsbio.com\/products\/cleaved-integrinalphav-hc-k889-polyclonal-antibody-bt-ap01933","provider":"AFSBio Inc.","version":"1.0","type":"link"}