{"product_id":"cleaved-parp-asp214-polyclonal-antibody-e-ab-93361","title":"Cleaved PARP (Asp214) Polyclonal Antibody - E-AB-93361","description":"\u003cp\u003eCleaved PARP (Asp214) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-93361-60, E-AB-93361-120, E-AB-93361-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Cleaved PARP (Asp214)\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1; PARP1; Cleaved PARP; PARP1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P09874\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human Cleaved PARP\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 113kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 89KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146695082163,"sku":"E-AB-93361-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146695114931,"sku":"E-AB-93361-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146695147699,"sku":"E-AB-93361-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_25a9d930-eedd-4c5b-b9d5-2ea4cadb10ed.png?v=1710300311","url":"https:\/\/afsbio.com\/products\/cleaved-parp-asp214-polyclonal-antibody-e-ab-93361","provider":"AFSBio Inc.","version":"1.0","type":"link"}