{"product_id":"cleaved-plasma-kallikrein-hc-r390-rabbit-pab-es1072","title":"Cleaved-Plasma Kallikrein HC (R390) rabbit pAb - ES1072","description":"\u003cp\u003eCleaved-Plasma Kallikrein HC (R390) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1072-50, ES1072-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human KLKB1. AA range:341-390\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 45kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3818\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P03952\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202000445619,"sku":"ES1072-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202000478387,"sku":"ES1072-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_eb5b3992-bdac-4bdb-8101-075158291212.png?v=1767119668","url":"https:\/\/afsbio.com\/products\/cleaved-plasma-kallikrein-hc-r390-rabbit-pab-es1072","provider":"AFSBio Inc.","version":"1.0","type":"link"}