{"product_id":"cleaved-plasminogen-hc-a-short-form-v98-rabbit-pab-es1073","title":"Cleaved-Plasminogen HC A short form (V98) rabbit pAb - ES1073","description":"\u003cp\u003eCleaved-Plasminogen HC A short form (V98) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1073-50, ES1073-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PLG; Plasminogen\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PLMN. AA range:79-128\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 54kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5340\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P00747\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted. Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202000511155,"sku":"ES1073-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202000543923,"sku":"ES1073-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_5ee464f3-f575-498b-b71f-071c98c74b48.png?v=1767119670","url":"https:\/\/afsbio.com\/products\/cleaved-plasminogen-hc-a-short-form-v98-rabbit-pab-es1073","provider":"AFSBio Inc.","version":"1.0","type":"link"}