{"product_id":"clk1-polyclonal-antibody-bt-ap01980","title":"CLK1 Polyclonal Antibody - BT-AP01980","description":"\u003cp\u003eCLK1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01980-20, BT-AP01980-50, BT-AP01980-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CLK1 encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein (CDC like kinase 1) phosphorylates serine\/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine\/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for CLK1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CLK1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CLK1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 57205\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49759; Mouse: P22518\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CLK1; CLK; Dual specificity protein kinase CLK1; CDC-like kinase 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1195; Mouse: 12747\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240217436339,"sku":"BT-AP01980-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240217469107,"sku":"BT-AP01980-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240217501875,"sku":"BT-AP01980-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e0aa7dc9-d0d9-4394-bae5-2437f5c61cd0.png?v=1769405239","url":"https:\/\/afsbio.com\/products\/clk1-polyclonal-antibody-bt-ap01980","provider":"AFSBio Inc.","version":"1.0","type":"link"}