{"product_id":"clk4-polyclonal-antibody-bt-ap01983","title":"CLK4 Polyclonal Antibody - BT-AP01983","description":"\u003cp\u003eCLK4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01983-20, BT-AP01983-50, BT-AP01983-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CDC like kinase 4 encoded by CLK4 belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5\/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CLK4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CLK4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 57492\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9HAZ1; Mouse: O35493\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CLK4; Dual specificity protein kinase CLK4; CDC-like kinase 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 57396; Mouse: 12750\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240217632947,"sku":"BT-AP01983-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240217665715,"sku":"BT-AP01983-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240217698483,"sku":"BT-AP01983-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2743fcf3-7a8d-4734-9f1b-28bd05f365ab.png?v=1769405242","url":"https:\/\/afsbio.com\/products\/clk4-polyclonal-antibody-bt-ap01983","provider":"AFSBio Inc.","version":"1.0","type":"link"}