{"product_id":"cmpk2-rabbit-polyclonal-antibody-es17365","title":"CMPK2 Rabbit Polyclonal Antibody - ES17365","description":"\u003cp\u003eCMPK2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES17365-50, ES17365-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human CMPK2 AA range: 57-107\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: CMPK2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of CMPK2 at Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Among all investigated tumors, leukemia cells show the most abundant expression,\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 49kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Pyrimidine metabolism, Metabolic pathways, Nucleotide metabolism, Biosynthesis of cofactors\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: ATP + (d)CMP = ADP + (d)CDP\u003cbr\u003e\nFunction: May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP, CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs\u003cbr\u003e\nSimilarity: Belongs to the thymidylate kinase family\u003cbr\u003e\nTissue Specificity: Among all investigated tumors, leukemia cells show the most abundant expression\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Mitochondrion\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: CMPK2\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: CMPK2\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 22169\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q3U5Q7\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315569873075,"sku":"ES17365-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315569905843,"sku":"ES17365-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/cmpk2-rabbit-polyclonal-antibody-es17365","provider":"AFSBio Inc.","version":"1.0","type":"link"}