{"product_id":"cntf-polyclonal-antibody-bt-ap07915","title":"CNTF Polyclonal Antibody - BT-AP07915","description":"\u003cp\u003eCNTF Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07915-20, BT-AP07915-50, BT-AP07915-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Neuroscience; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CNTF\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Ciliary neurotrophic factor\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P26441; Mouse: P51642; Rat: P20294\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Ciliary neurotrophic factor;CNTF; CNTF; Ciliary neurotrophic factor; CNTF\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1270\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239099654323,"sku":"BT-AP07915-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239099687091,"sku":"BT-AP07915-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239099719859,"sku":"BT-AP07915-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f197ef03-0630-4c10-9e74-4bc38a53619c.png?v=1769389110","url":"https:\/\/afsbio.com\/products\/cntf-polyclonal-antibody-bt-ap07915","provider":"AFSBio Inc.","version":"1.0","type":"link"}