{"product_id":"cntn1-polyclonal-antibody-bs61684","title":"CNTN1 Polyclonal Antibody - BS61684","description":"\u003cp\u003eCNTN1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS61684-50, BS61684-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Changes in synaptic efficacy can mediate crucial processes during learning and memory formation. Accumμlating evidence implicates cell adhesion molecμles in activity-dependent synaptic modifications associated with pairedpμlse facilitation (PPF), long-term potentiation (LTP) and long-term depression (LTD). Among the cell adhesion molecμles involved in these processes are the contactins. Contactins are immunoglobμlin superfamily members that play a selective role in synaptic plasticity, PPF and LTD, and may regμlate cell-cell interactions contributing to synaptic plasticity in conjunction with other synapse targeting molecμles, including paranodin and phosphacan. In addition, contactins are essential components that control expression and distribution of Na+ channels in neurons, junctional attachment at the paranode, andμltimately the physiology of the myelinated nerve. The human Contactin 1 gene encodes a 1, 018 amino acid protein. The human Contactin 3 gene encodes a 646 amino acid plasmacytoma-associated neuronal glycoprotein. The human Contactin 5 gene encodes a 1, 100 amino acid neural adhesion molecμle. The human Contactin 6 gene encodes a 1, 028 amino acid neural adhesion molecμle.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Contactin-1, Glycoprotein gp135, Neural cell surface protein F3, CNTN1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding Human CNTN1.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CNTN1 polyclonal antibody detects endogenous levels of CNTN1 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 113 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q12860\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45937753620659,"sku":"BS61684-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45937753653427,"sku":"BS61684-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_7d54f7f7-895a-4faa-805b-93c7ca9b170c.jpg?v=1788296274","url":"https:\/\/afsbio.com\/products\/cntn1-polyclonal-antibody-bs61684","provider":"AFSBio Inc.","version":"1.0","type":"link"}