{"product_id":"coenzyme-nad-rabbit-pab-a21048","title":"Coenzyme NAD Rabbit pAb - A21048","description":"\u003cp\u003eCoenzyme NAD Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A21048-20, A21048-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NAD+, as a key coenzyme in eukaryotic organisms, determines hundreds of enzymatic reactions. The coenzyme NAD is involved in oxidation–reduction reactions critical for glycolysis, fatty acid oxidation, the TCA cycle, and complex I of the mitochondrial respiratory chain and also is a key regulator of autophagy. In addition, NAD+ can also indirectly regulate the process of anti-stress, cell growth, anti-inflammatory and anti-aging processes by regulating the function of Sirtuins factor which has NAD+ dependent protein deacetylation activity. The decline of NAD+ level will also lead to heart failure and Alzheimer's disease.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: DB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Species independent\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: Refer to figures\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Chemical compounds corresponding to Coenzyme.\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: DB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Coenzyme NAD\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189373264051,"sku":"A21048-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189373296819,"sku":"A21048-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_3b3122f2-d360-4ce6-b925-8d5b5a858768.png?v=1766425703","url":"https:\/\/afsbio.com\/products\/coenzyme-nad-rabbit-pab-a21048","provider":"AFSBio Inc.","version":"1.0","type":"link"}