{"product_id":"cofilin-rabbit-polyclonal-antibody-ra23619","title":"Cofilin Rabbit Polyclonal Antibody - RA23619","description":"\u003cp\u003eCofilin Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA23619-50, RA23619-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: cofilin 1 (CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.76% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: IHC-p1:50-200 ,WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)\u003c\/p\u003e \n\n\u003cp\u003eApplications: IHC-p; WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 1072\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 19\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P23528\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121212940467,"sku":"RA23619-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121212973235,"sku":"RA23619-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_47b70f31-40f4-4864-92bc-8cf0098a2a67.png?v=1773345292","url":"https:\/\/afsbio.com\/products\/cofilin-rabbit-polyclonal-antibody-ra23619","provider":"AFSBio Inc.","version":"1.0","type":"link"}