{"product_id":"col17a1-polyclonal-antibody-ra21404","title":"COL17A1 Polyclonal Antibody - RA21404","description":"\u003cp\u003eCOL17A1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA21404-50, RA21404-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: collagen type XVII alpha 1 chain (COL17A1) Homo sapiens This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: COL17A1 BP180 BPAG2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 1308\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 150\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UMD9\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121064337587,"sku":"RA21404-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121064370355,"sku":"RA21404-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9cf3dba8-5187-41d1-8c79-da18dc90888c.png?v=1773370295","url":"https:\/\/afsbio.com\/products\/col17a1-polyclonal-antibody-ra21404","provider":"AFSBio Inc.","version":"1.0","type":"link"}