{"product_id":"col2a1-monoclonal-antibody-bt-mca4837","title":"COL2A1 Monoclonal Antibody - BT-MCA4837","description":"\u003cp\u003eCOL2A1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4837-50, BT-MCA4837-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: COL2A1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7G2C8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: COL2A1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human COL2A1 (AA: 1222-1487) expressed in HEK293-6e cells supernatant.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 141.8kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P02458\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AOM, ANFH, SEDC, STL1, COL11A3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1280\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238515761331,"sku":"BT-MCA4837-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238515794099,"sku":"BT-MCA4837-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_20b38113-e3fc-4f16-a323-8a658b92006b.png?v=1769381979","url":"https:\/\/afsbio.com\/products\/col2a1-monoclonal-antibody-bt-mca4837","provider":"AFSBio Inc.","version":"1.0","type":"link"}