{"product_id":"col2a1-monoclonal-antibody-e-ab-22275","title":"COL2A1 Monoclonal Antibody - E-AB-22275","description":"\u003cp\u003eCOL2A1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-22275-60, E-AB-22275-120, E-AB-22275-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: COL2A1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Alpha 1 type II collagen; Alpha-1 type II collagen; AOM; Cartilage collagen; Chondrocalcin; CO2A1; COL11A3; Col2a1; Collagen II alpha 1 polypeptide; SEDC\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC-p\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: Clone:8F6\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P02458\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide of Collagen II\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Protein A purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-300\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43135930564787,"sku":"E-AB-22275-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43135930597555,"sku":"E-AB-22275-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43135930630323,"sku":"E-AB-22275-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c1d5ff3d-c84d-42e4-baa7-fe76eff99766.png?v=1709986674","url":"https:\/\/afsbio.com\/products\/col2a1-monoclonal-antibody-e-ab-22275","provider":"AFSBio Inc.","version":"1.0","type":"link"}