{"product_id":"col2a1-polyclonal-antibody-bt-ap02080","title":"COL2A1 Polyclonal Antibody - BT-AP02080","description":"\u003cp\u003eCOL2A1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02080-20, BT-AP02080-50, BT-AP02080-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: COL2A1 encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in COL2A1 are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for COL2A1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: COL2A1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: COL2A1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 141785\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P02458; Mouse: P28481; Rat: P05539\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: COL2A1; Collagen alpha-1(II) chain; Alpha-1 type II collagen\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1280; Mouse: 12824; Rat: 25412\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240223563955,"sku":"BT-AP02080-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240223596723,"sku":"BT-AP02080-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240223629491,"sku":"BT-AP02080-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4446f045-980e-486e-902d-33925acd6d96.png?v=1769405329","url":"https:\/\/afsbio.com\/products\/col2a1-polyclonal-antibody-bt-ap02080","provider":"AFSBio Inc.","version":"1.0","type":"link"}