{"product_id":"collagen-ii-mouse-monoclonal-antibody-1h1-bt-mca0355","title":"Collagen II mouse Monoclonal Antibody (1H1) - BT-MCA0355","description":"\u003cp\u003eCollagen II mouse Monoclonal Antibody (1H1)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0355-20, BT-MCA0355-50, BT-MCA0355-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: COL2A1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Collagen alpha-1(II) chain\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P02458; Mouse: P28481; Rat: P05539\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Collagen alpha-1(II) chain; Alpha-1 type II collagen\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1280\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240034853043,"sku":"BT-MCA0355-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240034885811,"sku":"BT-MCA0355-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240034918579,"sku":"BT-MCA0355-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e27c13dd-aacb-4ac2-8c8b-088365f6ad84.png?v=1769402460","url":"https:\/\/afsbio.com\/products\/collagen-ii-mouse-monoclonal-antibody-1h1-bt-mca0355","provider":"AFSBio Inc.","version":"1.0","type":"link"}