{"product_id":"cop-ζ1-i48-polyclonal-antibody-bs3287","title":"COP ζ1 (I48) Polyclonal Antibody-BS3287","description":"\u003cp\u003eCOP ζ1 (I48) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3287-50, BS3287-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P61923\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ1 subunits (also known as β-COP, γ-COP, δ-COP and ζ-1 COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, COPP and COPE subunits (also known as α-COP, COPP and ε-COP, respectively).\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: COP ζ1 (I48) polyclonal antibody detects endogenous levels of COP ζ1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 20 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of COP ζ1 (I48) polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: Hela cell lysate\u003cbr\u003e\n Lane 2: HEK293T cell lysate\u003cbr\u003e\n Lane 3: sp2\/0 cell lysate\u003cbr\u003e\n Lane 4: H9C2 cell lysate\u003cbr\u003e\n Lane 5: PC12 cell lysate, Immunohistochemistry (IHC) analyzes of COP ζ1 (I48) pAb in paraffin-embedded human esophageal carcinoma tissue at 1:5000. Nucleus speckle and Cytoplasm staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase., Immunohistochemistry (IHC) analyzes of COP ζ1 (I48) pAb in paraffin-embedded human stomach carcinoma tissue at 1:5000. Nucleus speckle and Cytoplasm staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Coatomer subunit zeta-1; Zeta-1-coat protein; Zeta-1 COP; COPZ1; COPZ; CGI-120; HSPC181; COP ζ-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to the N-terminus of Human COP ζ1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993797726387,"sku":"BS3287-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993797759155,"sku":"BS3287-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_17b19d77-d923-47ec-ab4c-701850b7d0cd.jpg?v=1706183672","url":"https:\/\/afsbio.com\/products\/cop-%ce%b61-i48-polyclonal-antibody-bs3287","provider":"AFSBio Inc.","version":"1.0","type":"link"}