{"product_id":"cox10-polyclonal-antibody-ra23711","title":"COX10 Polyclonal Antibody - RA23711","description":"\u003cp\u003eCOX10 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA23711-50, RA23711-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor (COX10) Homo sapiens Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lys\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: COX10; Protoheme IX farnesyltransferase; mitochondrial; Heme O synthase\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 1352\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 49\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q12887\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121217134771,"sku":"RA23711-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121217167539,"sku":"RA23711-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_df4e9544-d92b-4ede-adc7-6f2525897651.png?v=1773345348","url":"https:\/\/afsbio.com\/products\/cox10-polyclonal-antibody-ra23711","provider":"AFSBio Inc.","version":"1.0","type":"link"}