{"product_id":"cox4-polyclonal-antibody-bt-ap15077","title":"COX4 Polyclonal Antibody - BT-AP15077","description":"\u003cp\u003eCOX4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15077-20, BT-AP15077-50, BT-AP15077-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3andapos; of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: COX4I1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P13073; Mouse: P19783; Rat: P10888\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1327\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239103127731,"sku":"BT-AP15077-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239103160499,"sku":"BT-AP15077-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239103193267,"sku":"BT-AP15077-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_61e44cea-653d-40fe-b241-8fcdb095de23.png?v=1769389153","url":"https:\/\/afsbio.com\/products\/cox4-polyclonal-antibody-bt-ap15077","provider":"AFSBio Inc.","version":"1.0","type":"link"}