{"product_id":"cox4i2-monoclonal-antibody-bt-mca0381","title":"COX4I2 Monoclonal Antibody - BT-MCA0381","description":"\u003cp\u003eCOX4I2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0381-50, BT-MCA0381-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Metabolism; Tags and; cell markers; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: COX4I2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM, IF, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cytochrome c oxidase subunit 4 isoform 2 mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96KJ9; Mouse: Q91W29\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: COX4I2; COX4L2; Cytochrome c oxidase subunit 4 isoform 2; mitochondrial; Cytochrome c oxidase subunit IV isoform 2; COX IV-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 84701\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238684942515,"sku":"BT-MCA0381-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238684975283,"sku":"BT-MCA0381-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9a29de85-0ef6-4586-a47f-9ab84caa216a.png?v=1769383758","url":"https:\/\/afsbio.com\/products\/cox4i2-monoclonal-antibody-bt-mca0381","provider":"AFSBio Inc.","version":"1.0","type":"link"}