{"product_id":"cp3a5-polyclonal-antibody-bt-ap08041","title":"CP3A5 Polyclonal Antibody - BT-AP08041","description":"\u003cp\u003eCP3A5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08041-20, BT-AP08041-50, BT-AP08041-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CYP3A5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cytochrome P450 3A5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P20815\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cytochrome P450 3A5;EC 1.14.14.1;CYPIIIA5;Cytochrome P450 HLp2;Cytochrome P450-PCN3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1577\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239103717555,"sku":"BT-AP08041-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239103750323,"sku":"BT-AP08041-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239103783091,"sku":"BT-AP08041-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_397f249e-6d12-4d3f-b104-9b026a9db5d4.png?v=1769389160","url":"https:\/\/afsbio.com\/products\/cp3a5-polyclonal-antibody-bt-ap08041","provider":"AFSBio Inc.","version":"1.0","type":"link"}