{"product_id":"creatine-kinase-b-monoclonal-antibody-mb66873","title":"Creatine Kinase B Monoclonal Antibody-MB66873","description":"\u003cp\u003eCreatine Kinase B Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66873-50, MB66873-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P12277\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens .Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa . Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation .During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work .\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of Creatine Kinase B protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Creatine Kinase B expression in MDAMB453 (A), 293 (B), Y79 (C), mouse stomach (D), mouse brain (E) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 42 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CKBB; Creatine kinase B-type; B-CK; Creatine kinase B chain\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human Creatine Kinase B. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906390888627,"sku":"MB66873-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906390921395,"sku":"MB66873-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a944b1d0-d369-4fbb-a341-fe0fe9078b6f.jpg?v=1702918974","url":"https:\/\/afsbio.com\/products\/creatine-kinase-b-monoclonal-antibody-mb66873","provider":"AFSBio Inc.","version":"1.0","type":"link"}