{"product_id":"crem-polyclonal-antibody-bt-ap02223","title":"CREM Polyclonal Antibody - BT-AP02223","description":"\u003cp\u003eCREM Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02223-20, BT-AP02223-50, BT-AP02223-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CREM\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CREM Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 37006\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q03060; Mouse: P27699; Rat: Q03061\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1390; Mouse: 12916; Rat: 25620\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240233820339,"sku":"BT-AP02223-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240233853107,"sku":"BT-AP02223-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240233885875,"sku":"BT-AP02223-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6fcffd4a-cf61-46c4-939c-2c601cc86d08.png?v=1769405486","url":"https:\/\/afsbio.com\/products\/crem-polyclonal-antibody-bt-ap02223","provider":"AFSBio Inc.","version":"1.0","type":"link"}