{"product_id":"crm1-acetyl-lys568-rabbit-pab-es1133","title":"CRM1 (Acetyl Lys568) rabbit pAb - ES1133","description":"\u003cp\u003eCRM1 (Acetyl Lys568) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1133-50, ES1133-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 125kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7514\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O14980\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus\/nucleolus and the cytoplasm.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202003493043,"sku":"ES1133-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202003525811,"sku":"ES1133-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_530ffc31-b074-4a1d-b909-db097971c5c2.png?v=1767119737","url":"https:\/\/afsbio.com\/products\/crm1-acetyl-lys568-rabbit-pab-es1133","provider":"AFSBio Inc.","version":"1.0","type":"link"}