{"product_id":"crmp1-polyclonal-antibody-e-ab-12333","title":"CRMP1 Polyclonal Antibody - E-AB-12333","description":"\u003cp\u003eCRMP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-12333-60, E-AB-12333-120, E-AB-12333-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CRMP1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Collapsin response mediator protein 1; CRMP 1; CRMP-1; Crmp1; Dihydropyrimidinase like 1; Dihydropyrimidinase related protein 1; Dihydropyrimidinase-related protein 1; DPYL1; DPYSL1; DRP 1; DRP-1; DRP1; ULIP-3; Ulip3; Unc-33-like phosphoprotein 3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q14194\u003c\/p\u003e\n\n\u003cp\u003eBackground: Collapsin response mediator protein 1, encoded by theCRMP1gene, is a humanproteinof theCRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human CRMP1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 62kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136223707315,"sku":"E-AB-12333-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136223740083,"sku":"E-AB-12333-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136223772851,"sku":"E-AB-12333-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_bb1970a1-4a87-4453-8066-41fe10efcf01.png?v=1709988419","url":"https:\/\/afsbio.com\/products\/crmp1-polyclonal-antibody-e-ab-12333","provider":"AFSBio Inc.","version":"1.0","type":"link"}