{"product_id":"crocc-polyclonal-antibody-bt-ap15108","title":"CROCC Polyclonal Antibody - BT-AP15108","description":"\u003cp\u003eCROCC Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15108-20, BT-AP15108-50, BT-AP15108-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis.,PTM:Phosphorylated by NEK2 which may regulate its association with centrosomes. Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the rootletin family.,subcellular location:In ciliated cells, associated with ciliary rootlets. In non-ciliated cells, localized between, around and at the proximal ends of the centrioles. Dissociates from the centrioles at the onset of mitosis and reassociates with them at anaphase.,subunit:Homopolymer. Interacts with KLC3, NEK2 and the N-terminus of CEP250.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags and cell markers\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: CROCC\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Rootletin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q5TZA2; Mouse: Q8CJ40\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Rootletin;Ciliary rootlet coiled-coil protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9696\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239106994355,"sku":"BT-AP15108-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239107027123,"sku":"BT-AP15108-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239107059891,"sku":"BT-AP15108-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0fa5a9ca-65f7-417c-8b0d-6618db448b31.png?v=1769389204","url":"https:\/\/afsbio.com\/products\/crocc-polyclonal-antibody-bt-ap15108","provider":"AFSBio Inc.","version":"1.0","type":"link"}