{"product_id":"cry1-polyclonal-antibody-bt-ap15110","title":"CRY1 Polyclonal Antibody - BT-AP15110","description":"\u003cp\u003eCRY1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15110-20, BT-AP15110-50, BT-AP15110-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK\/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER\/CRY heterodimers to interact with CLOCK\/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CRY1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cryptochrome-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q16526; Mouse: P97784; Rat: Q32Q86\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cryptochrome-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1407\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239107223731,"sku":"BT-AP15110-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239107256499,"sku":"BT-AP15110-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239107289267,"sku":"BT-AP15110-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_96cf2b1c-d5ad-4de2-8e67-440e6092d84c.png?v=1769389211","url":"https:\/\/afsbio.com\/products\/cry1-polyclonal-antibody-bt-ap15110","provider":"AFSBio Inc.","version":"1.0","type":"link"}