{"product_id":"csk-monoclonal-antibody-mb0131","title":"Csk Monoclonal Antibody-MB0131","description":"\u003cp\u003eCsk Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB0131-50, MB0131-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P41240\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:1000\u003cbr\u003e\nICC: 1:50\u003c\/p\u003e\n\n\u003cp\u003eBackground: C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of Csk and does not cross-react with related proteins.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Predicted band size: 50KDa\u003cbr\u003e\nObserved band size: 50KDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot detection of CSK antibody in C6 and Jurkat cell lysates using CSK antibody (1:1000 diluted)., Immunocytochemistry staining of C6 cells fixed by anhydrous methanol for 2 h at -20℃ and using anti-CSK antibody (dilution 1:50).\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human Csk.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989565837491,"sku":"MB0131-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989565870259,"sku":"MB0131-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5bc4d3ff-f46a-4c5f-ada2-24dd5a9864c2.jpg?v=1706095475","url":"https:\/\/afsbio.com\/products\/csk-monoclonal-antibody-mb0131","provider":"AFSBio Inc.","version":"1.0","type":"link"}