{"product_id":"csk22-polyclonal-antibody-bt-ap15113","title":"CSK22 Polyclonal Antibody - BT-AP15113","description":"\u003cp\u003eCSK22 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15113-20, BT-AP15113-50, BT-AP15113-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53\/TP53 following UV irradiation.,Belongs to the protein kinase superfamily. Ser\/Thr protein kinase family. CK2 subfamily.,Contains 1 protein kinase domain.,subunit:Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CSNK2A2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Casein kinase II subunit alpha'\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P19784; Mouse: O54833\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Casein kinase II subunit alpha';CK II alpha';EC 2.7.11.1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1459\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239107649715,"sku":"BT-AP15113-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239107682483,"sku":"BT-AP15113-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239107715251,"sku":"BT-AP15113-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_63c55414-5b02-44c6-9e99-34e7471a58bc.png?v=1769389213","url":"https:\/\/afsbio.com\/products\/csk22-polyclonal-antibody-bt-ap15113","provider":"AFSBio Inc.","version":"1.0","type":"link"}