{"product_id":"ctcfl-polyclonal-antibody-e-ab-61825","title":"CTCFL Polyclonal Antibody - E-AB-61825","description":"\u003cp\u003eCTCFL Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61825-60, E-AB-61825-120, E-AB-61825-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CTCFL\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CTCFL; BORIS; CT27; CTCF-T; HMGB1L1; dJ579F20.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q8NI51\u003c\/p\u003e\n\n\u003cp\u003eBackground: CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human CTCFL\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 35kDa\/46-80kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 83KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146205167795,"sku":"E-AB-61825-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146205233331,"sku":"E-AB-61825-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146205266099,"sku":"E-AB-61825-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_048cc398-6512-411b-9ca7-24878423d609.png?v=1710291738","url":"https:\/\/afsbio.com\/products\/ctcfl-polyclonal-antibody-e-ab-61825","provider":"AFSBio Inc.","version":"1.0","type":"link"}