{"product_id":"ctip-phospho-ser327-rabbit-polyclonal-antibody-ra23878","title":"CTIP (Phospho Ser327) Rabbit Polyclonal Antibody - RA23878","description":"\u003cp\u003eCTIP (Phospho Ser327) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA23878-50, RA23878-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RB binding protein 8, endonuclease (RBBP8) Homo sapiens The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and\/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: DNA endonuclease RBBP8 (EC 3.1.-.-;CtBP-interacting protein;CtIP;Retinoblastoma-binding protein 8;RBBP-8;Retinoblastoma-interacting protein and myosin-like;RIM;Sporulation in the absence of SPO11 protein 2 homolog;SAE2)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5932\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 100\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q99708\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121223721139,"sku":"RA23878-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121223753907,"sku":"RA23878-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ac2d357c-9dbc-41cc-a82d-7153b307dd3b.png?v=1773345415","url":"https:\/\/afsbio.com\/products\/ctip-phospho-ser327-rabbit-polyclonal-antibody-ra23878","provider":"AFSBio Inc.","version":"1.0","type":"link"}