{"product_id":"ctip2-polyclonal-antibody-bs90342","title":"Ctip2 Polyclonal Antibody-BS90342","description":"\u003cp\u003eCtip2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90342-50, BS90342-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9C0K0\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB IHC IF ICC ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t 1:500 - 1:2000\u003cbr\u003e\nIHC\t 1:100 - 1:500\u003cbr\u003e\nIF\t 1:100 - 1:500\u003cbr\u003e\nICC  1:100 - 1:500\u003cbr\u003e\nELISA 1:5000 - 1:10000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)\/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL\/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6. 0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes;Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Ctip2) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 95 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Ctip2 polyclonal antibody detects endogenous levels of Ctip2 protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: B cell lymphoma\/leukemia 11B; B-cell CLL\/Lymphoma 11B; B-cell lymphoma\/leukemia 11B; BC11B_HUMAN; BCL-11B; Bcl11B; COUP-TF interacting protein 2; COUP-TF-interacting protein 2; Ctip 2; hRit1; MS1029; Radiation induced tumor suppressor gene 1; Radiation induced tumor suppressor gene 1 protein; Radiation-induced tumor suppressor gene 1 protein; Rit 1; Rit1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human Ctip2 : 331-4630\/894\u003c\/p\u003e \n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939196407987,"sku":"BS90342-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939196440755,"sku":"BS90342-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3eb1acc4-6ea1-405c-8d43-7aee12a9e97c.jpg?v=1704544890","url":"https:\/\/afsbio.com\/products\/ctip2-polyclonal-antibody-bs90342","provider":"AFSBio Inc.","version":"1.0","type":"link"}