{"product_id":"cttn-monoclonal-antibody-bt-mca3466","title":"CTTN Monoclonal Antibody - BT-MCA3466","description":"\u003cp\u003eCTTN Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3466-50, BT-MCA3466-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq)\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CTTN\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4C6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CTTN\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CTTN expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 80kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q14247\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: EMS1, FLJ34459, CTTN\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2017\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238608363699,"sku":"BT-MCA3466-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238608396467,"sku":"BT-MCA3466-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a0943ae3-2927-4314-a3fb-1c3c6f87761d.png?v=1769383024","url":"https:\/\/afsbio.com\/products\/cttn-monoclonal-antibody-bt-mca3466","provider":"AFSBio Inc.","version":"1.0","type":"link"}