{"product_id":"cxcr-3-polyclonal-antibody-bt-ap02329","title":"CXCR-3 Polyclonal Antibody - BT-AP02329","description":"\u003cp\u003eCXCR-3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02329-20, BT-AP02329-50, BT-AP02329-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9\/Mig (monokine induced by interferon-g), CXCL10\/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11\/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for CXCR3. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4\/PF4 (PMID:12782716).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CXCR3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CXCR-3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 40660\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49682; Mouse: O88410\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CXCR3; GPR9; C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; CKR-L2; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor; CD antigen CD183\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2833\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240240308403,"sku":"BT-AP02329-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240240341171,"sku":"BT-AP02329-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240240373939,"sku":"BT-AP02329-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_850c4975-d595-4c14-bea5-3da4b07aff11.png?v=1769405579","url":"https:\/\/afsbio.com\/products\/cxcr-3-polyclonal-antibody-bt-ap02329","provider":"AFSBio Inc.","version":"1.0","type":"link"}