{"product_id":"cxcr3-b-rabbit-pab-a25216","title":"CXCR3-B Rabbit pAb - A25216","description":"\u003cp\u003eCXCR3-B Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A25216-20, A25216-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9\/Mig (monokine induced by interferon-g), CXCL10\/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11\/I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4\/PF4 (PMID:12782716) .\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 45kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 43kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2833\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P49682-2\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R; CXCR3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway, Neuroscience, Calcium Signaling, Cardiovascular.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CXCR3-B\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189866881203,"sku":"A25216-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189866913971,"sku":"A25216-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_dff72a7b-aebd-486d-b38a-80eca6c9074f.png?v=1766437065","url":"https:\/\/afsbio.com\/products\/cxcr3-b-rabbit-pab-a25216","provider":"AFSBio Inc.","version":"1.0","type":"link"}