{"product_id":"cxcr3-polyclonal-antibody-bs90349","title":"CXCR3 Polyclonal Antibody-BS90349","description":"\u003cp\u003eCXCR3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90349-50, BS90349-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49682(Human)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB:1:500-1:2,000\u003cbr\u003e\nICC:1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The C-X-C or α chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has since been shown to function as a potent chemoattractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). CXCR-3, also known as IP-10\/MIG receptor, mediates Ca2+ mobilization and chemotaxis in response to the C-X-C chemokines IP-10 and MIG. CXCR-3 is highly expressed in IL-2-activated T lymphocytes, but not in resting T lymphocytes, B lymphocytes, monocytes or granulocytes.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CXCR3 polyclonal antibody detects endogenous levels of CXCR3 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 41 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of CXCR3 on Hela cell using anti-CXCR3 antibody at 1\/1,000 dilution., ICC staining CXCR3 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CXC-R3, CXCR-3, IP-10 receptor, IP-10 receptor, CD183, CXCR3, GPR9, C-X-C chemokine receptor type 3, CD 183, CD182, CD183, Chemokine (C X C motif) receptor 3, Chemokine (C X C) receptor 3, Chemokine CXC Motif Receptor 3, CKR L2, CKR-L2, CKRL2, CMKAR3, CXC-R3, CXCR-3, CXCR3, CXCR3, G Protein Coupled Receptor 9, G protein-coupled receptor 9, GPR9, Interferon-inducible protein 10 receptor, IP-10 receptor, IP10, IP10 R, IP10 receptor, IP10-R, IP10R, Mig R, Mig receptor, Mig-R, MIGR,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979802775731,"sku":"BS90349-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979802808499,"sku":"BS90349-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_85a9d1ee-64d1-4c1f-a28d-8a9a089440bc.jpg?v=1705752877","url":"https:\/\/afsbio.com\/products\/cxcr3-polyclonal-antibody-bs90349","provider":"AFSBio Inc.","version":"1.0","type":"link"}