{"product_id":"cyclin-d1-rabbit-monoclonal-antibody-bs40006","title":"Cyclin D1 Rabbit Monoclonal Antibody-BS40006","description":"\u003cp\u003eCyclin D1 Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40006-50, BS40006-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P24385\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB, IHC ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB 1:1000~1:5000 IHC 1:50~1:200 ICC\/IF 1:50~1:100 IP 1:50\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB\/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Cyclin D1 Antibody detects endogenous levels of total Cyclin D1\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 35 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Cyclin D1 Rabbit monoclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: MCF-7 whole cell lysate (30ug)\u003cbr\u003e\n Lane 2: A431 whole cell lysate (30ug)\u003cbr\u003e\n Lane 3: The Liver tissue lysate of Mouse (30ug)\u003cbr\u003e\n Lane 4: The Lung tissue lysate of Rat (30ug), Immunohistochemical analysis of paraffin-embedded human bladder, using Cyclin D1 Antibody., Immunofluorescent analysis of MCF-7 cells, using Cyclin D1 Antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CCND1; BCL1; D11S287E; PRAD1; U21B31; Cyclin D1;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Cyclin D1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993808539827,"sku":"BS40006-50","price":276.71,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993808572595,"sku":"BS40006-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_be8a3fa8-34c1-41ab-8455-b9af7b6fcf96.jpg?v=1706183790","url":"https:\/\/afsbio.com\/products\/cyclin-d1-rabbit-monoclonal-antibody-bs40006","provider":"AFSBio Inc.","version":"1.0","type":"link"}