{"product_id":"cyclin-e2-monoclonal-antibody-bs65503","title":"Cyclin E2 Monoclonal Antibody-BS65503","description":"\u003cp\u003eCyclin E2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65503-50, BS65503-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: NULL\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: Flow-Cyt=2ug\/Test \u003cbr\u003e\nnot yet tested in other applications.\u003cbr\u003e\noptimal dilutions\/concentrations should be determined by the end user.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 \/ S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 \/ Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of proliferating normal and neoplastically transformed cells, Cyclin E2 levels are low to undetectable in non transformed cells and increase significantly in neoplasm derived cells.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Cyclin E2 monoclonal Antibody detects endogenous levels of Cyclin E2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~44 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CCN E2;  CCNE 2;  CCNE2;  CCNE2 protein;  CYC E2;  CYCE 2;  CYCE2;  CyclinE2;  G1\/S-specific cyclin E2;  G1\/S-specific cyclin E2;  CCNE2_HUMAN.\u003c\/p\u003e  \n\n\u003cp\u003eImmunogen: Recombinant human Cyclin E2 protein, around C-terminal 100aa:\u003c\/p\u003e \n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42899702612147,"sku":"BS65503-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42899702644915,"sku":"BS65503-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0c518a18-ac39-4c37-aa22-2adfe17485d0.jpg?v=1702661294","url":"https:\/\/afsbio.com\/products\/cyclin-e2-monoclonal-antibody-bs65503","provider":"AFSBio Inc.","version":"1.0","type":"link"}