{"product_id":"cyclin-e2-monoclonal-antibody-mb10789","title":"Cyclin E2 Monoclonal Antibody-MB10789","description":"\u003cp\u003eCyclin E2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB10789-50, MB10789-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O96020\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 \/ S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 \/ Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Cyclin E2 in Jurkat lysates using Cyclin E2 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Cyclin E2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of Cyclin E2 in MCF-7 using Cyclin E2 antibody, and DAPI\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CCNE2; G1\/S-specific cyclin-E2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human Cyclin E2\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43004733292723,"sku":"MB10789-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43004733325491,"sku":"MB10789-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_883a9c77-fefb-42ab-90c7-73b0986ac8e0.jpg?v=1706444948","url":"https:\/\/afsbio.com\/products\/cyclin-e2-monoclonal-antibody-mb10789","provider":"AFSBio Inc.","version":"1.0","type":"link"}