{"product_id":"cyclin-h-monoclonal-antibody-mb0018","title":"Cyclin H Monoclonal Antibody-MB0018","description":"\u003cp\u003eCyclin H Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB0018-50, MB0018-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P51946\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IP,\u003c\/p\u003e  \n\n\u003cp\u003eAll Applications: WB: 1:1000\u003cbr\u003e\nIP: 1:50~1:200\u003c\/p\u003e \n\n\u003cp\u003eBackground: Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of CCNH and does not cross-react with related proteins\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Predicted band size: 38KDa\u003cbr\u003e\nObserved band size: 38KDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot detection of Cyclin H in Jurkat, K562 and A431 cell lysates using Cyclin H antibody (1:1000 diluted)., Immunoprecipitation analysis of Hela cell lysates using Cyclin H antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cyclin-H; MO15-associated protein; p34; p37; CCNH\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human Cyclin H.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42987087167667,"sku":"MB0018-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42987087233203,"sku":"MB0018-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_7237dcd2-3f64-4b77-bc47-819831cdaef0.jpg?v=1706008856","url":"https:\/\/afsbio.com\/products\/cyclin-h-monoclonal-antibody-mb0018","provider":"AFSBio Inc.","version":"1.0","type":"link"}