{"product_id":"cyclin-h-phospho-t315-polyclonal-antibody-bs64522","title":"Cyclin H (Phospho-T315) Polyclonal Antibody-BS64522","description":"\u003cp\u003eCyclin H (Phospho-T315) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS64522-50, BS64522-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P51946\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500~1:1000 IHC:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Cyclin H (Phospho-T315) polyclonal antibody detects endogenous levels of Cyclin H protein only when phosphorylated at Thr315.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 37 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Cyclin H (Phospho-T315) polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane A: Hela whole cell lysate\u003cbr\u003e\nLane B: H1688 whole cell lysate\u003cbr\u003e\nLane C: The Liver tissue lysate of Mouse\u003cbr\u003e\nLane D: The Liver tissue lysate of Rat\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cyclin-H; MO15-associated protein; p34; p37; CCNH\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic phosphopeptide derived from human Cyclin H around the phosphorylation site of Threonine 315.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43044028776627,"sku":"BS64522-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43044028809395,"sku":"BS64522-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c6246ed7-e3f7-43b5-9aff-9207b4c443b5.jpg?v=1707738664","url":"https:\/\/afsbio.com\/products\/cyclin-h-phospho-t315-polyclonal-antibody-bs64522","provider":"AFSBio Inc.","version":"1.0","type":"link"}