{"product_id":"cyfp1-polyclonal-antibody-bt-ap15151","title":"CYFP1 Polyclonal Antibody - BT-AP15151","description":"\u003cp\u003eCYFP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15151-20, BT-AP15151-50, BT-AP15151-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA.,Belongs to the CYFIP family.,subcellular location:Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.,subunit:Interacts with the active GTP-bound form of RAC1. Interacts with FMR1\/FMRP but does not bind to related proteins FXR1 or FXR2. Component of the WAVE2 complex composed of ABI1, CYFIP1\/SRA1, NCKAP1\/NAP1 and WASF2\/WAVE2 (By similarity). Interacts through its C-terminus with the C-terminus of DPYSL2\/CRMP2 which is necessary for DPYSL2-induced axon outgrowth.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CYFIP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cytoplasmic FMR1-interacting protein 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q7L576; Mouse: Q7TMB8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cytoplasmic FMR1-interacting protein 1;Specifically Rac1-associated protein 1;Sra-1;p140sra-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23191\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239112663219,"sku":"BT-AP15151-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239112695987,"sku":"BT-AP15151-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239112728755,"sku":"BT-AP15151-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_583e19ac-7c04-4bf8-a103-996b662d73de.png?v=1769389275","url":"https:\/\/afsbio.com\/products\/cyfp1-polyclonal-antibody-bt-ap15151","provider":"AFSBio Inc.","version":"1.0","type":"link"}