{"product_id":"cyfp1-polyclonal-antibody-ra31899","title":"CYFP1 Polyclonal Antibody - RA31899","description":"\u003cp\u003eCYFP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA31899-50, RA31899-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA.,similarity:Belongs to the CYFIP family.,subcellular location:Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.,subunit:Interacts with the active GTP-bound form of RAC1. Interacts with FMR1\/FMRP but does not bind to related proteins FXR1 or FXR2. Component of the WAVE2 complex composed of ABI1, CYFIP1\/SRA1, NCKAP1\/NAP1 and WASF2\/WAVE2 (By similarity) . Interacts through its C-terminus with the C-terminus of DPYSL2\/CRMP2 which is necessary for DPYSL2-induced axon outgrowth.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 23191\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 137\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q7L576\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120452427955,"sku":"RA31899-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120452460723,"sku":"RA31899-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d8cde1e1-dabf-4fc6-bd83-608fc7bfe0f8.png?v=1773365816","url":"https:\/\/afsbio.com\/products\/cyfp1-polyclonal-antibody-ra31899","provider":"AFSBio Inc.","version":"1.0","type":"link"}